CONTENTS

In Japanese


—Symposium Reviews—

Moral Dilemmas of Pharmacists and the Importance of the Ethical Education
……… Y. Shimodozono 783
The Present Status and the Future Issues of the Ethics Education in the Department of Pharmacy
……… Y. Hayase 785
Moral Dilemmas of the Pharmacist-Ways of Coping with Ethical Problems in Light of Case Studies-
……… K. Kawamura 793
What Kind of Ethical Education for Pharmacists is Necessary?-Can “The Core Curriculum Model for Pharmacology Education” Provide the Needed Guidance?-
……… J. Matsuda 807

—Reviews—

Evaluation of Induction of Drug-metabolizing Enzyme mRNAs in Primary Cultures of Cryopreserved Human and Cynomolgus Monkey Hepatocytes
……… M. Nishimura 815
Personalized Optimization of β-lactam Regimens Based on Studies of the Pharmacokinetics-pharmacodynamics at the Target Sites
……… K. Ikawa 821

—Regular Articles—

Dose Estimation for Renal-excretion Drugs in Neonates and Infants Based on Physiological Development of Renal Function
……… S. Suzuki, Y. Murayama, E. Sugiyama, M. Sekiyama, and H. Sato 829
Preliminary Study to Identify the Predictive Factors for the Response to Methotrexate Therapy in Patients with Rheumatoid Arthritis
……… S. Inoue, M. Hashiguchi, K. Takagi, S. Kawai, and M. Mochizuki 843
Evaluation of Tetrandrine Sustained Release Calcium Alginate Gel Beads In Vitro and In Vivo
……… Y. Ma, W.-Z. Li, S.-X. Guan, X.-P. Lai, and D.-W. Chen 851
Z-ligustilide Extracted from Radix Angelica Sinensis Decreased Platelet Aggregation Induced by ADP Ex Vivo and Arterio-venous Shunt Thrombosis In Vivo in Rats
……… L. Zhang, J.-R. Du, J. Wang, D.-K. Yu, Y.-S. Chen, Y. He, and C.-Y. Wang 855
Gastroprotective and Antioxidant Effects of Opipramol on Indomethacin-induced Ulcers in Rats
……… H. Dursun, F. Albayrak, M. Bilici, F. Koc, H. H. Alp, T. Candar, and O. Kukula 861
Effects of Various Diuretics on Cardiac Function in Rats with Heart Failure
……… H. Tanaka, K. Watanabe, M. Harima, P. V. Thanikachalam, K. Yamaguchi, H. Tachikawa, M. Kodama, and Y. Aizawa 871

—Articles—

Determination of Total Ash and Acid-insoluble Ash of Chinese Herbal Medicine Prunellae Spica by Near Infrared Spectroscopy
……… Y. Rao and B. Xiang 881
Search for Consciousness of Hospital Pharmacists on the Future Prospects of their Practices and on their Practices of Blood Drawing or Injection
……… M. Koinuma, Y. Imai, M. Kanda, K. Koike, Y. Miyazaki, T. Sato, and H. Nakamura 887