CONTENTS

In Japanese


—Regular Articles—

Role of the Nitric Oxide on Relaxation of the Human Umbilical Artery during Cooling
………K. E. Nurullahoğlu Atalık, Z. Ü. Nurullahoğlu, and M. Kılıç 661
Investigation of the Factors that Contribute to the Onset of Insomnia in Hypertensive Patients by Using a Post-marketing Surveillance Database
………N. Tanabe, T. Fujita, Y. Fujii, and T. Orii 669
Furanocoumarins Contents and Cytochrome P450 3A (CYP3A) Inhibitory Activities of Various Processed Fruit Peel Products: Outflow of 6',7'-Dihydroxybergamottin during Processing Treatment of Peel
………M. Ishihara, H. Toda, N. Sunagane, and T. Ohta 679
Use of Anonymous Web Communities and Websites by Medical Consumers in Japan to Research Drug Information
………K. Kishimoto and N. Fukushima 685
Enteric Microsphere Formulations of Papain for Oral Delivery
………M. Sharma, V. Sharma, A. K. Panda, and D. K. Majumdar 697
Dissolution Characteristics of Composite Particles Using a Spray Freeze Drying
………M. Kondo, T. Niwa, and K. Danjo 711
HPLC Determination of Strychnine and Brucine in Rat Tissues and the Distribution Study of Processed Semen Strychni
………J. Chen, T. Hou, Y. Fang, Z. Chen, X. Liu, H. Cai, T. Lu, G. Yan, and B. Cai 721
Mechanism of Pigmentation by Minocycline in Murine B16 Melanoma Cells
………E. Sato, M. Tsukimoto, N. Shimura, A. Awaya, and S. Kojima 731
Alpha Lipoic Acid Treatment Improved Endothelium-dependent Relaxation in Diabetic Rat Aorta
………N. Okudan, K. E. Nurullahoğlu Atalık, H. Gökbel, A. Canbilen, and I. Kara 739
Analysis of Body Constitution of Fifty-two Patients with Stevens-Johnson Syndrome (SJS) Using Kampo Medical Questionnaires: Prediction of SJS based on Body Constitution Using Decision Tree
………S. Ohshima, Y. Hatori, S. Honma, K. Terasawa, Y. Saitoh, and D. Kobayashi 745
Selective Elimination of the Transformed Hepatic Stem Cells Using Hybrid Liposomes
………A. Oshikata, R. Miyazaki, T. Matsushita, and R. Ueoka 757
Detailed Analysis of Clinical Test Data on Chemotherapy for Colorectal Cancer
………N. Sotoishi, K. Yoshimatsu, H. Yokomizo, T. Katsube, J. Nishimura, S. Yakou, K. Ogawa, and K. Takayama 765
Experimental Therapeutic Effects of Hybrid Liposomes on the Alzheimer's Disease in Vitro
………K. Zako, M. Sakaguchi, Y. Komizu, H. Ichihara, K. Goto, Y. Matsumoto, and R. Ueoka 775
An Opinion Survey about Purchasing Nonprescription Drugs over the Internet in Remote Islands—Survey among Internet-literate Inhabitants—-
………T. Hirayama, H. Tanaka, S. Suzuki, H. O-mura, M. Nagase, S. Sakumoto, M. Sugahara, T. Kitahara, C. Miyazaki, N. Yamashita, K. Yoshitani, A. Miki, H. Satoh, S. Hori, and Y. Sawada 783

—Notes—

Influence of Mineral Water on Absorption of Oral Alendronate in Rats
………Y. Akagi, T. Sakaue, E. Yoneyama, and T. Aoyama 801
Development of Rapid Genotyping Methods for Single Nucleotide Polymorphisms of Cytochrome P450 2C9 (CYP2C9) and Cytochrome P450 2C19 (CYP2C19) and Their Clinical Application in Pediatric Patients with Epilepsy
………Y. Yamamoto, Y. Takahashi, S. Nishimura, Y. Ikumi, N. Mishima, and Y. Kagawa 809
Covariance Structure Analysis of Pharmacists' Attitudes toward Medication History
………H. Sato and Y. Shimamori 817
Simple and Rapid Screening for Methamphetamine and 3,4-Methylenedioxymethamphetamine (MDMA) and Their Metabolites in Urine Using Direct Analysis in Real Time (DART)-TOFMS
………M. Kawamura, R. Kikura-Hanajiri, and Y. Goda 827
Surveillance Study on Use of Over-the-Counter Drug and Health Food by School Pharmacist for Grade-schooler, Junior High School Student, and High School Students
………M. Anraku, H. Tomida, E. Sato, N. Tabuchi, H. Yoshitomi, N. Okamura, K. Taguchi, Y. Kondo, and N. Murakami 835
A Research Survey on the Information Gathering Methods, Attitudes, and Requests from Care Managers about the Pharmaceutical Service by Pharmacists in Home Care
………Y. Nanaumi, M. Onda, H. Sakurai, R. Tanaka, K. Tsubota, S. Matoba, Y. Mukai, Y. Arakawa, and Y. Hayase 843

—Article—

Effect of Nonsteroidal Anti-inflammatory Drugs on Pharmacokinetics of Methotrexate: A Meta-analysis
………Y. Uwai, R. Suzuki, and K. Iwamoto 853
Errata
……… 862