CONTENTS

In Japanese


—Reviews—

Investigation on Traditional Medicines of Guarany Indio and Studies on Diterpenes from Scoparia dulcis
………T. Hayashi 1259
Drug Discovery by Formulation Design and Innovative Drug Delivery Systems (DDS)
………H. Okada 1271
Novel Approach to Curatives of Mibyou (Presymptomatic Diseases)
………T. Miyata 1289
Inhibition Mechanism of Trypsin by Schiff Base Metal Chelate Inhibitors
………D. Iyaguchi 1299
Mass Spectrometry-based Quantitative Analysis and Biomarker Discovery
………N. Suzuki 1305
Functional Glutamate Signaling in Neural Progenitor Cells
………N. Nakamichi 1311
Effect of Environmental Factor Influencing the Development of Mouse Cerebral Cortex
………H. Fukumitsu 1317
Novel Iodocyclization Method Based on the Controlling of Oxidative Aromatization
………T. Okitsu 1323
Molecular Regulation of Muscle Stem Cells by `Quiescence Genes'
………S. Fukada 1329
Optimization of Adenovirus Vectors for Transduction in Embryonic Stem Cells and Induced Pluripotent Stem Cells
………K. Tashiro 1333
Metal-free Direct Biaryl Coupling Reaction of Heteroaromatic Compounds via Iodonium Intermediate
………K. Morimoto 1339
Drug Discovery for Improvement of Chronic Kidney Disease and Cardiovascular Disease
………K. Ishizawa 1347

—Regular Articles—

Development of an Online Incident-reporting System for Management of Medical Risks at Hospital
………H. Kanda 1353
Evaluation of Brilliance and Visibility of Fluorescence and Chemiluminescence Solution for Training of Preparing Injections
………S. Ishiwata, A. Taga, H. Sano, M. Kobayashi, J. Nomiyama, S. Harada, A. Kita, M. Takada, and R. Sugiura 1361
Effects of Implementation of Problem-based Learning Tutorials on Fifth-year Pharmacy Students and Future Issues
………A. Sato, M. Morone, and Y. Azuma 1369
Induction of Caspase-3-Dependent Apoptosis in Human Leukemia HL-60 Cells by δ-Elemene
………J. Ying, W. Yang, C.-Y. Xie, Q.-C. Ni, X.-D. Pan, J.-H. Dong, Z.-M. Liu, and X.-S. Wang 1383

—Note—

Effect of Hemopurification Rate on Doripenem Pharmacokinetics in Critically Ill Patients Receiving High-flow Continuous Hemodiafiltration
………Y. Ohchi, S. Hidaka, K. Goto, R. Shitomi, T. Nishida, T. Abe, S. Yamamoto, N. Yasuda, S. Hagiwara, and T. Noguchi 1395