CONTENTS

In Japanese


—Symposium Reviews—

Facing Challenges for Drug Discovery Using Molecular Display Technology and Combinatorial Bioengineering
……… S. Shibasaki and M. Ueda 1275
Novel High-Throughput System for Production of New Medicines-Integration and Combination with Molecular Display and Combinatorial Bioengineering
……… M. Ueda 1277
Research and Development of Combinatorial Bioengineering Using Zebrafish and Its Application on Drug Discovery
……… Y. Tamaru 1285
Applications of the Motif-programmed Proteins in Medical Area
……… K. Shiba 1295
Beyond Antibodies: Generation of Conformationally Constrained Peptides for Molecular-Targeting Therapy
……… I. Fujii 1303
Rational Fragment-design Method Based on a Thermodynamic Analysis
……… K. Tsumoto and M. Ui 1311
Protein Display onto Nano-sized Bacterial Magnetic Particles for Receptor Analysis
……… T. Yoshino and T. Matsunaga 1319
Generation of Mucosal Vaccine Utilizing Lactobacillus Display System
……… T. Sewaki 1327
Development of Platform Technology Using Molecular Display
……… S. Shibasaki 1333

—Reviews—

Intestinal Absorption and Secretion Mechanism of Carboxylate Drugs
……… S. Itagaki 1341
Individual Differences of Drug-metabolizing Enzymes as Determinants for the Metabolic Fate of Chemicals -A Study of Trimethylamine and Flavin-containing Monooxygenase 3-
……… M. Shimizu 1351
Dosing Time Based on Molecular Mechanism of Biological Clock of Hepatic Drug Metabolic Enzyme
……… N. Matsunaga 1357

—Regular Articles—

Introducing Hazard Prediction Training ‘KYT’ to Undergraduate Pharmacy Education on Patient Safety
……… Y. Murai, M. Sato, H. Yamaguchi, M. Shimada, N. Mano, J. Goto, and T. Hishinuma 1367
Evaluation of Diclofenac Sodium Release from Matrix Pellets Compressed into MUPS Tablets
……… B. Ivić, S. Ibrić, G. Betz, and Z. Djurić 1375
Incompatibility of Ceftriaxone Sodium with Calcium-containing Products
……… Y. Nakai, E. Tokuyama, M. Yoshida, and T. Uchida 1385
The Attitude Survey of Medical Staff on the Participation of Community Pharmacists in the Palliative Home Care
……… N. Akai, W. Fujita-Hamabe, and S. Tokuyama 1393
Cell Apoptosis Induced by δ-Elemene in Colorectal Adenocarcinoma Cells via a Mitochondrial-mediated Pathway
……… C.-Y. Xie, W. Yang, M. Li, J. Ying, S.-J. Tao, K. Li,J.-H. Dong, and X.-S. Wang 1403
Cilostazol Induces Metallothionein Expression in Vascular Cells
……… Y. Fujiwara, T. Kitagawa, Y. Shinkai, T. Kaji, and M. Satoh 1415

—Notes—

Hormone Excretion and Peroxisomes of Human Immortalized Extravillous Trophoblast Cells (TCL-2) Derived from First-Trimester Placenta
……… F. Hashimoto, A. Ono, K. Matsuoka, S. Yokota, H. Seki, S. Takeda, and H. Hayashi 1423